Mesothelioma and Work Exposure Mesothelioma is more prevalent in people who work with asbestos. Those who do construction jobs firefighters, military veterans or firefighters are at a higher risk. Mesothelioma mostly affects the lung's lining (pleural mesothelioma) or the abdomen. In rare cases, it may affect the heart or testicles. https://vimeo.com/704908941