Conolidine’s analgesic effects stem from its interaction with non-opioid pain pathways. Contrary to opioids, which bind to µ-opioid receptors from the central nervous system, conolidine modulates alternate molecular targets. A Science Improvements examine observed that conolidine interacts Along with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availabil... https://conolidine-treat-knee-pai12346.develop-blog.com/45311599/alternative-natural-pain-relief-to-replace-traditional-painkillers-an-overview